About Oxford BioResource

The Oxford BioResource is a research facility of the University of Oxford and the Oxford University Hospitals NHS Trust which provides infrastructure to underpin biobank activities.

 The biospecimens and associated information are used for research studies that aim to contribute to increasing the knowledge and understanding of disease in order to improve diagnosis and treatment and could ultimately lead to improvements in patient care. 

 Aims of Oxford BioResource

  • Facilitate access to human samples, data and related services in accordance with ethical and regulatory standards.
  • Operate a multi-site Human Tissue Authority Research Licence with policies and procedures in place to ensure regulatory compliance.
  • Assist with establishing new sample collections.
  • Work with new and existing collections to ensure regulatory compliance by conducting regular audits and sharing of best practice.
  • Provide practical assistance and guidance to researchers looking to establish new tissue collections for translational research.
  • Give advice and guidance on ethical requirements for the use of human tissue in research.
  • Aim to represent specific biobanking initiatives across Oxford.

Infrastructure and resources underpinning Oxford BioResource

Pulling together infrastructure based across the University of Oxford and Oxford University Hospitals NHS Trust has ensured we can provide the services needed by biomedical scientists. At the core of the resource are a number of key assets.

  • Nuffield Department of Surgical Sciences Bio-repository – a service-driven research facility offering sample banking, automated formatting, storage and retrieval services.
  • Oxford BioBank – a large population of individuals from Oxfordshire who have consented for re-approach participation in studies exploring the genetic basis of disease.
  • Oxford Gastrointestinal Illness Biobank – a collection of biological samples and associated data from patients undergoing assessment and treatment for GI disease.
  • Oxford Molecular Diagnostics Centre – providing state-of-art molecular diagnostics, sequencing and pathology expertise.
  • Oxford Musculoskeletal Biobank - a licensed Research Tissue Bank geared towards supporting musculoskeletal research.
  • Oxford Radcliffe Biobank – a licensing and governance body enabling access to general pathology tissue and biobanking services for ethically approved research.
  • Oxford Transplant Institute - a group of biobanks designed to help research focused on improving the quality and outcome of organ transplants with comprehensive blood, urine and tissue samples collected during the donor management period and recipient clinical care. 

Oxford BioResource also aims to represent many of the disease specific biobanking initiatives running within Oxford to promote collaborations and further research in important areas such as dementia and viral infections. 

Governance

The governance structure of the Oxford BioResource comprises a Steering Committee, a Human Tissue Act 2004 (HTA) Advisory Committee, and an Operational management team. The Steering Committee oversees governance and provides ethical, scientific and strategic direction. The HTA committee provides direction to the people working under the HTA research licence 12217 to ensure regulatory compliance.