Oxford BioBank

The Oxford BioBank is a randomised population-based cohort of individuals who have consented to be re-approached for recruit-by-genotype or phenotype translational research. Possessing data for more than 7,300 individuals of working age, the resource provides an excellent platform to explore how genes and the environment influence health outcomes.

While most biobanks collect genetic material, Oxford BioBank complements genetic data with comprehensive anthropometric and biochemistry profiling to enable researchers to study health and illness in greater detail. Due to the richness of data, Oxford BioBank has attracted use by several genome-wide association studies.

As a prominent resource within the National Institute for Health Research (NIHR) BioResource initiative, Oxford BioBank continues to recruit individuals willing to participate in this valuable platform. For more information on how to become involved as a participant visit the Oxford Biobank website.

Resource Details

  • Exome chip control cohort of 5,500 men and women aged 30-50, completely anonymised for research users. Affimetrix High Density array data on 7,300 men and women available from Autumn 2015. 
  • Re-approach consent in place.
  • Comprehensive anthropometric and biochemistry data collected during a clinic visit, including (but not limited to) Dual-Energy X-ray absorptiometry (n=5,800), advanced diabetes/obesity and cardiovascular biochemistry, hCRP, IGF-1, IGFBP1 and fasting insulin concentrations.
  • Blood pressure is measured in everyone.
  • The ability to identify cases using genetic or phenotypic criteria.

Access

Oxford BioBank encourages use by research groups internal and external to the University of Oxford and Oxford University Hospitals Trust. To gain access a written proposal must be made through the Oxford Biobank website. The resource is directed by Professor Fredrik Karpe.